Interesting Article: Antipsychotic Efficacy

I ran across a quite interesting article this past week that had been recently published in the Lancet.

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Leucht S, et.al., Lancet. 2013 Sep 14;382(9896):951-62. doi: 10.1016/S0140-6736(13)60733-3.

This is a meta-analysis of randomized trials comparing 15 different anti-psychotics and asking the questions:

1. Which is the most effective antipsychotic in treating schizophrenia?
2. Which antipsychotic has the most (and least) number of side effects?

The answers are quite interesting. Unless you are a psychiatrist, you may not have intuitively known this information before. Continue reading